CALCIUM (CITRATE/MALATE) are the calcium salts of citric and malic acid. These chelated forms of calcium are water-soluble compounds and therefore are highly absorbable and bioavailable. Calcium is the most abundant mineral in the body with the majority of body reserves being in the bones and teeth. Depletion of bone calcium occurs when blood levels of calcium are below optimal level. This repeated borrowing of bone calcium can lead to porous bone tissues and increases the risk for fractures and breakage. Although much of bone mass is acquired during adolescence and early adulthood, maintaining adequate intake of calcium throughout life can have profound effects on enhancing bone density. In studies of post-menopausal women, oral calcium supplementation has been shown to reduce bone loss and fractures.†

MAGNESIUM (CITRATE) is a chelated form of magnesium and is also well absorbed and bioavailable. Magnesium is the fourth most abundant mineral in the body and supports numerous functions including enzyme regulation, calcium transport, and parathyroid hormone activity. Magnesium is also a critical component of the structure of the bone matrix, and deficiency is linked to an increase in bone brittleness and fracture risk. It is estimated that nearly 60% of the U.S. population does not meet the RDA for magnesium, leading to possible negative effects on cardiovascular, neurological, and bone health. Studies have shown that magnesium supplementation among post-menopausal women can support bone density and help prevent bone turnover.†

VITAMIN K2 (MENAQUINONE-7) supports bone health with its essential role in modulation of aberrant calcium metabolism. Arterial calcification is a major risk factor for both cardiovascular disease and osteoporosis. Vitamin K2 has a unique
role as a dependent cofactor for carboxylation of the human matrix GLA protein (MGP), a major inhibitor of arterial calcification. Vitamin K2 as menaquinone-7 has been shown effective for maintaining calcium balance by helping keep calcium in the bones and out of the vascular media.†

GLUCOSAMINE HCL is one of several naturally occurring amino sugars that are necessary for the rebuilding and healthy maintenance of connective tissue, including tendons, ligaments, cartilage, and bone matrix. Increased age is associated with glycation of cartilage that reduces the production of proteoglycans involved as joint lubricants. Glucosamine is an essential component of proteoglycans and may be nutritionally required to re-establish proteoglycan levels. A meta-analysis of fifteen double-blind, placebo-controlled clinical trials revealed that glucosamine sulfate was superior to placebo in all fifteen studies. Patients receiving glucosamine sulfate have a gradual and progressive reduction in joint pain and tenderness, as well as improved range of motion and walking speed. Glucosamine HCl is stabilized with either sodium chloride or potassium chloride. Our glucosamine product is stabilized with potassium chloride to avoid an additional source of sodium for patients.†... Click here to continue reading